The evidence surrounding levels of proteinuria and clinical outcome is conflicting.
This study suggests that it is the presence of proteinuria that confers an increase in perinatal risk on the pregnancy.
Renal damage was confirmed by the presence of proteinuria in older mice.
The controversy for proteinuria is how to detect it and at what level of proteinuria should action be taken.
All had gestational hypertension with no evidence of multisystem disease apart from gestational proteinuria.
All studies agree that as the degree of proteinuria increases there is a greater variation in the protein/creatinine ratio over time.
Some studies suggest a proportional link between the level of proteinuria and adverse clinical outcome.
It is possible that there is a microalbuminuric phase that precedes overt proteinuria in preeclampsia and that we might devise strategies to detect this.
