0 a type of B vitamin essential for cell growth and reproduction:
folate deficiency/levels
All patients should be started on folic acid replacement as folate requirements increase during haemolytic processes.
The latter is more a reflection of recent folate intake.
Results suggest that intracellular folate levels are highly regulated in accordance with embryonic growth and development, whilst extracellular folate levels are dependent on gestational age.
Low folate status has been implicated in carcinogenesis, possibly as a result of a higher rate of genetic damage.
Since dietary folate supplementation was proven to prevent specific congenital malformations, including around 70% of neural tube defects, possible mechanisms have been investigated.
We found that embryos cultured in the presence of folate antagonists such as 5-fluorouracil and cycloleucine have a deranged suppression test, as predicted.
Abstracts of papers folate-deficient and the normal diet group have been analysed for comparison.
Here, we describe 3 further genes in the folate pathway.
