Exempel på folate

• All patients should be started on folic acid replacement as folate requirements increase during haemolytic processes.

• The latter is more a reflection of recent folate intake.

• Results suggest that intracellular folate levels are highly regulated in accordance with embryonic growth and development, whilst extracellular folate levels are dependent on gestational age.

• Low folate status has been implicated in carcinogenesis, possibly as a result of a higher rate of genetic damage.

• Since dietary folate supplementation was proven to prevent specific congenital malformations, including around 70% of neural tube defects, possible mechanisms have been investigated.

• We found that embryos cultured in the presence of folate antagonists such as 5-fluorouracil and cycloleucine have a deranged suppression test, as predicted.

• Abstracts of papers folate-deficient and the normal diet group have been analysed for comparison.

• Here, we describe 3 further genes in the folate pathway.

• The measures may be used in combination and would probably be more effective if folate supplementation could also be included.

• Excessive alcohol intake is associated with reduced serum folate levels.

• Abstracts of papers likely to have a role in folate catabolism.

• Does dietary folate intake modify effect of alcohol consumption on breast cancer risk?

• Further to this, intracellular and extracellular folate levels have been measured in neurulation-stage embryos to specifically examine how the maternal folate-deficient diet affects embryonic folate metabolism.

• Herbert (1962) had his food finely chopped and boiled three times to remove all folate.

• Folate intake and risk of breast cancer characterized by hormone receptor status.