Exempel på amyloidosis

• Familial atypical generalized amyloidosis with special involvement of the peripheral nerves.

• Death can result from infections, haemophagocytosis, renal or cardiac amyloidosis, or myocardial infarction.

• A chronic abnormality of the immune system is the mechanism frequently proposed for the pathogenesis of the amyloidosis.

• Vitreous amyloidosis associated with homozygosity for the transthyretin methionine-30 gene.

• A role for destabilizing amino acid replacements in light chain amyloidosis.

• However, even during symptom-free intervals, these patients can be shown to have an intermediate degree of biological inflammation, which increases the risk of amyloidosis.

• Secondary autonomic failure may be associated with diabetes, chronic renal and hepatic failure, connective tissue disorders, amyloidosis, demyelinating polyneuropathies, multiple sclerosis and brainstem lesions.

• Meningocerebrovascular amyloidosis associated with a novel transthyretin mis-sense mutation at codon-18.

• Other important single-gene angiopathies, such as hereditary cerebral haemorrhage with amyloidosis, caused by mutations in the amyloid precursor protein gene may also occur.

• The nature of the particular amyloidosis is dependent on the protein involved.

• Proposed mechanism for lysozyme amyloidosis.

• Localized dystrophic amyloidosis of heart valves.

• We, therefore, studied 20 calcified mitral valves from patients with chronic rheumatic disease presenting moderate to severe inflammatory infiltrate, 15 of them with amyloidosis and the otherfivewithout amyloid.

• Such conditions include emphysema, bronchitis, tuberculosis, bronchiectasis, amyloidosis, pneumonia, cystic fibrosis, chronic obstructive pulmonary disease, and pulmonary fibrosis.

• In 2011, he was treated for amyloidosis, a blood disorder.