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No biomarker was incorporated into the study to help validate the disease-modifying effect.
Molecular biology techniques based on the specificity of biological recognition (bio-affinity) have been extensively developed for biomarker detection (nucleic acids, proteins, lipids, other metabolites).
This suggests that small amounts of kerogen may be used as a biomarker for silicified filamentous features composed primarily of oxide minerals.
Progress in the field of biomarker development has been substantial over the past few years.
The majority of these studies have employed proteomics as a tool for biomarker discovery rather than for the exploration of underlying molecular mechanisms.
Unfortunately, the coverage was brief and confined to ' ' conventional ' ' planetary instrumentation only, but nonetheless stressed the difficult nature of biomarker definition.
Various concentrations of b-carotene in the matrix were investigated to determine the detection limits of this biomarker.
A good biomarker is difficult to make inorganically.