Acetylcholine increases pulmonary blood flow in intact fetuses via endothelium-dependent vasodilation.
Beraprost, therefore, is a safe and effective vasodilator which provides preferential pulmonary vasodilation in infants and children with pulmonary hypertension secondary to congenital heart disease.
The vasodilation correlated negatively with levels of free haemoglobin.
In contrast, no vasodilation could be demonstrated in "nonresponsive" patients (p=.23).
The only persistent side effect is hypotension, most likely related to vasodilation.
They may also induce vasodilation independently via different mediator pathways.
Hot environments exacerbate cutaneous vasodilation and increase fluid loss through sweating.
Accordingly, the selectivity of pulmonary vasodilation may be overestimated in the setting of loading with nitric oxide.
