In the fourth inning, he pinch-ran and broke up a double play the hard way; i.e., by taking the errant relay throw to first flush on the noggin.
Noggin plays a key role in cartilage and bone patterning.
This is significant because when only noggin is deficient there are mild defects but the head still forms.
In developing mice that are deficient in both chordin and noggin, the head is nearly absent.
Examples of neural inducers are the molecules noggin and chordin.
Axial mesoderm cells under the ectoderm secrete inhibitory signals called chordin, noggin and follistatin.
In mice in which noggin is lacking, there are fewer hair follicles than on a normal mouse and the development of the follicle is inhibited.
The noggin was first mentioned in the mid 17th century, initially as the cup, and later coming to mean a quarter gill.