At present, these will perhaps be considered in cases with hypersensitivity and intolerability to conventional drugs.
Other mechanisms that could potentially cause cognitive decline are autoimmune vasculitis or allergic hypersensitivity responses to the chemotherapeutic medications.
Abnormalities in visual function have been documented in subjects suffering from primary headaches, with a demonstrated hypersensitivity to light in migraine patients.
A deficit in the transient system therefore has some of the same consequences as a hypersensitivity in the sustained system.
Rare patients present penicillin hypersensitivity, and there are some recorded instances of severe reaction, even including death.
Orthostatic hypotension, carotid sinus hypersensitivity and vasosagal syncope occur as isolated diagnoses in younger patients but occur in combination in older patients.
These correlations between behavioral and biochemical observations indicate that protein phosphorylation plays a key role in the initiation of central sensitization and, subsequently, pain hypersensitivity.
In this study, we have shown that this visceral hypersensitivity is also associated with microglial activation.
