Double-blinded assessment of the intervention is particularly important in this context, due to the subjective nature of pain and of some of the global outcome measures used.
The drug was injected under the skin (subcutaneous delivery) in a randomized double-blinded placebo-controlled trial this is the gold standard way of conducting a clinical trial.
The experiment was double-blinded, all bracelets were wrapped with tape so no one present knew which bracelet was real and which were fakes.
Anonymity may be unilateral or reciprocal (single- or double-blinded reviewing).
Clinical trials are often double-blinded so that the researchers also do not know which test subjects are receiving the active or placebo treatment.
In randomized, double-blinded trials, individuals on different dopamine agonists, including dihydroergocryptine, did not differ in discontinuation rate associated with adverse events.
More recently, a double-blinded, placebo-controlled trial focusing on women found that creatine, when used along with an antidepressant, exerted a powerful and rapid antidepressant effect.
Trials are typically randomized and double-blinded, with two (statistically) identical groups of patients being compared.
