0 A double-blind study or trial, especially in medicine, is one in which two groups of people are studied, for example with one group taking a new drug and one group taking something else, but neither the people in the study nor the scientist or doctor knows which person is in which group. --
1 used to describe a test of a new product, especially a medicine, in which one group of people is given the new product, and another group is given something that contains none of the product. Neither those being tested nor those doing the testing know which group is which: --
In the case of chemotherapy, placebos and double-blind situations are usually employed to ensure that an observed effect is directly attributable to the treatment.
An example is the insistence on double-blind randomized clinical trials for the rigorous comparison of interventions.
Subject and scorer bias is easily controlled by double-blind designs.
This practice continues today, as we solicit at least three referee reports for each article as part of the double-blind peer-review process.
These function structures were then graded for quality using a double-blind system.
There were no psychometric score differences between treatment groups after 3 months of double-blind treatment.
A randomized double-blind controlled trial in normal subjects.
Such compromise of the integrity of the double-blind in a clinical trial could lead to spurious results or an exaggeration of the treatment effect.