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Of the nine that coroners had finished investigating, two were caused directly by mephedrone.
In addition to its stimulant effects, mephedrone produces side effects, of which teeth grinding is the most common.
Mephedrone administration caused about a 500% increase in dopamine, and about a 950% increase in serotonin.
Of those who had already used mephedrone prior to the ban, 75% had continued to use it after the ban.
Firstly, dealers knew there was still demand for mephedrone, but were aware the supplies may be exhausted in the future.
They concluded more experimental research is needed to investigate the toxicity of mephedrone.
Due to its similarity to mephedrone, it is thought to be a stimulant and entactogen drug of the phenethylamine, amphetamine, and cathinone chemical classes.
It became available online in 2010 and has been sold as replacement for 4-methylmethcathinone (mephedrone).
I fear that the only message that will be sent by the hasty decision on mephedrone is that the drug laws deserve no respect.
In 2010, as its use became more prevalent, many countries passed legislation prohibiting mephedrone.
In another case, a 19-year-old male was admitted to hospital suffering from inflammation of the heart, 20 hours after taking one gram of mephedrone.
Because 4-methylephedrine can be obtained in a specific enantiomeric form, mephedrone consisting of only one enantiomer can be produced.
Mephedrone was first synthesized in 1929, but did not become widely known until it was rediscovered in 2003.
This is the enzyme involved in the processing of amphetamines of the cathinone group, including mephedrone and khat.
Around 50% of users reported at least one negative effect associated with the use of mephedrone, of which teeth grinding is the most common.
