Exempel på melanoma

• The psychosocial impact of other forms of cancer, including melanoma and lymphoma, has been investigated to a lesser degree.

• For example, patients with rectal cancer may report more negative outcome expectations for talking about illness and treatment side effects than patients with melanoma.

• Malignant melanoma and skin lymphoma are also important tumours in the elderly.

• By comparing genetic profiles, researchers were able to differentiate between benign naevi, primary melanomas and metastatic melanomas.

• Etiologic pathogenesis of melanoma: a unifying hypothesis for the missing attributable link.

• Lesions with any of the major features or three minor features are suspicious for melanoma and should be assessed by a specialist.

• A 28 year-old man with widespread melanoma is hoping the doctor will offer him a new treatment.

• Such transplanted melanoma and the resulting clinical metastases cause death in half the recipients.

• Complete removal of spingholipids from the plasma membrane disrupts cell to substratum adhesion of mouse melanoma cells.

• A major issue was the lack of uniformity in the histopathologic nomenclature for early melanoma and related lesions.

• In this context, research into the immunopathomechanisms in vitiligo might play an important part in the development of effective therapies for melanoma.

• A number of groups are investigating the use of tagged, tumour-specific antibodies and vaccines to melanoma.

• Most metastatic melanoma patients eventually die of brain metastases.

• Major progress in defining the molecular alterations associated with the evolution of melanoma came in 2002, through a systematic genome-wide assessment of cancer-associated pathways.

• Once invasion occurs, usually appearing clinically as a nodule, treatment and prognosis are no different from other melanomas.