Exempel på leukaemia

• Good evidence for a significant role exists for acute myeloid leukaemia and myeloma, but the role in solid tumours remains unclear.

• During this latter stage, differentiation is apparently blocked, and the clonal, nonfunctional, proliferating blast cells accumulate to cause a clinical disease similar to acute leukaemia.

• Removal of leukaemia inhibitory factor from the medium causes these cells to differentiate into embryoid bodies.

• Malignant blood disorders with associated anaemia, such as myelodysplasia and leukaemia, become more frequent with advancing age.

• He fought bravely against his leukaemia and tried as long as possible to maintain his scientific activity.

• Some of the earliest were antifolates, chemically modified to increase their effectiveness in treating childhood leukaemias.

• Prior conflicting results were obtained from leukaemia-derived cell lines, arrested at a single stage of haematopoiesis, and appear to be cellline-specific.

• An example might be a cluster of leukaemia cases near a nuclear power plant.

• Median survival for early-stage chronic lymphatic leukaemia and indolent follicular lymphomas is in the order of 10 years.

• An example of this is the occurrence of acute myeloid leukaemia in patients with myelodysplasia.

• Every parent grieves for the death of their children from leukaemia.

• Risk factors in the remaining three patients were : chronic myelogenous leukaemia, immunosuppression for renal transplant, and hyperglycaemia induced by corticosteroid used for temporal arteritis.

• A replication-defective retroviral vector based on the murine leukaemia virus is genetically modified to encode the human c sequence.

• However, such an approach would be possible in a limited number of tumour types, such as leukaemia, where repeated sampling of the tumour was feasible.

• The median age of acute myeloid leukaemia at diagnosis is over 60 years.