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Both parents were heterozygotes for PK deficiency.
In areas where malaria is common, heterozygotes have a strong selective advantage.
If all heterozygotes have the same fitness, then the rare chromosome doubles in frequency in every generation.
In our experiment, overdominant mutations will be scored as beneficial because we are scoring heterozygotes.
The loss in successful outcross pollen in the heterozygote is then compensated by a gain in outcrossed ovules.
These loci were not statistically dependent with no apparent heterozygote deficit or excess.
We assume that all mutations segregating in the population are equally deleterious and have equivalent fitness effects in heterozygotes.
Selection against heterozygotes is also unlikely because deviations were detected for 3 of the 6 polymorphic loci analysed.
This is within the limits of uncertainty as regards the number of possible heterozygote carriers within our female population.
Specifically we investigate levels of heterozygote deficit in the genotypes of oocysts from multiply infected mosquitoes.
Populations reach a quasi-equilibrium, with mean fitness and heterozygote and homozygote number fluctuating around deterministic equilibrium levels.
Polymorphism from environmental heterogeneity : models are only robust if the heterozygote is close in fitness to the favoured homozygote in each environment.
This deviation was always towards a deficit of heterozygotes.
The most important problem seems to be how the heterozygote of mutant alleles belonging to the same locus produced wild-type progeny.
This might be expected when haploids are compared with heterozygotes, but not necessarily expected when haploids are compared with homozygous mutant diploids.
On the potential for estimating the effective number of breeders from heterozygote-excess in progeny.
Estimating the effective number of breeders from heterozygote excess in progeny.
The heterozygote deficiencies were even higher in the other two species.
