Exempel på chromosomal

• This proposed model transfers murine findings to the human orthologous chromosomal region.

• As such it was done without chromosomal replication : two haploids recombined their genomes and then separated as haploids again.

• Point mutations in key regulatory genes, epigenetic changes, abnormal chromosome numbers and chromosomal rearrangements are frequently observed in tumour cells.

• Indeed, such changes might be as important as the more widely studied genetic mutations and chromosomal aberrations that characterise tumour cells.

• However, even this estimation may not be free from bias, especially when there are closely linked selected loci present in a short chromosomal region.

• To date 24 chromosomal loci have been mapped, 11 chromosomal aberrations verified and 17 of the genes identified.

• Many genetic studies are limited to big chromosomal segments and subsequent elaborated molecular genetic analyses.

• These other chromosomal anomalies occur less frequently and often cause death in infancy.

• The disorders range from chromosomal to neurocutaneous disorders and metabolic and infectious diseases.

• This is called "linkage mapping," because the existence of recombination allows us to "map" potential risk genes to specific chromosomal locations.

• The quadruplets of nuclear envelope (arrowheads) are assembled around clumped chromosomal bivalents.

• Placental volume measured by threedimensional ultrasound at 11 to 13 + 6 weeks of gestation: relation to chromosomal defects.

• The balancer procedure allows comparisons of the values of fitness components for chromosomal homozygotes and heterozygotes.

• Chromosomal mosaicism throughout human preimplantation development in vitro: incidence, type and relevance to embryo outcome.

• This is predominantly because of the high incidence of chromosomal or other structural anomalies associated with diaphragmatic hernia.