Exempel på amphetamine

• He had predicted at baseline that he would experience verbal hallucinations as part of the amphetamine experience.

• Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine.

• It was found that they had similar rates of offending but the amphetamine users' weekly expenditure on drugs was much lower.

• Amphetamine-induced hyperactivity is the most established rodent model for mania; this hyperactivity is attenuated by a number of mood stabilizers including lithium, anticonvulsants, and antipsychotics.

• There is considerable overlap in the mechanisms of action of methylphenidate and amphetamines, but there is a significant difference.

• Amphetamine-associated hallucinations are phenomenologically like those in schizophrenia.

• The amphetamine model psychosis provides the "look and feel" of paranoid schizophrenia and nests nicely with the dopamine hypothesis of schizophrenia.

• Each animal received only one drug, except those who received amphetamine followed by haloperidol.

• A significant subset are helped by amphetamines rather than methylphenidate.

• Although both methylphenidate and amphetamines inhibit reuptake of dopamine and norepinephrine, only amphetamines also promote release of those neurotransmitters.

• Hallucinations and loss of insight, associated with amphetamine, seem more schizophrenia-like.

• Orthostatic hypotension may be related to amphetamine-like metabolites.

• Evidence that amphetamine with physical therapy promotes recovery of motor function in stroke patients.

• A role of forebrain dopamine systems in amphetamine-induced and stereotyped behavior in the rat.

• The loss of insight and other behavioral effects with amphetamine can be very impressive.