The cultured follicles developed an antrum, demonstrating that the follicles survived.
Once the follicle has accumulated a few thousand granulosa cells, a fluid-filled cavity becomes apparent in the extracellular space; this is the antrum.
Effects of varying gonadotrophin dose and timing on antrum formation and ovulation efficiency of mouse follicles in vitro.
The oocyte is excentric and there is a dark area where the antrum could form.
This resulted in a mean final diameter of 471 + 7 m with a high proportion (89%) of antrum formation and healthy appearing oocytes.
Unexpected oocyte growth after follicular antrum formation in four marsupial species.
The physical barrier properties of healthy growing follicles can be evaluated by measuring the penetration of plasma proteins in the antrum as a function of their concentration in blood.
Reversal of anionisation, however, restores their capacity to freely enter the antrum once again.
