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Many studies suggest alpha-stat and alkaline-stat strategy as a preferred management prior to circulatory arrest and during the period of rewarming.
They stated that alpha stat regulation provides normal "flow/metabolic coupling" in the adult, but that in children the appropriate strategy is less clear.
The alpha-stat strategy was achieved by using 100% oxygen as the gas mixture.
The alpha-stat technique of management is used predominantly in cardiac surgery.
We recommend flow rates above 25% of normal, alpha-stat strategy, and pulsatile assistance for better protection of the brain during profound hypothermia.
Although alpha-stat regulation has been believed to maintain coupling, cerebral blood flow becomes increasingly luxuriant at lower temperatures in children using alpha-stat regulation.
We continue to use the alpha-stat strategy for older children and adults undergoing continuous cardiopulmonary bypass with mild or moderate hypothermia.
The stat, in short, is not necessarily the most appropriate way of securing compliance.