Tiredness, lethargy, dyspnoea, pruritus, insomnia, weakness and deterioration in mobility are common and have significant impact on the quality of life.
They postulated therefore that prurigo of pregnancy may arise as a result of pruritus gravidarum occurring in atopic women.
During the early stages of the infection, clinical symptoms include persistent limbic pain and pruritus at the bite site and paraesthesiae.
Aquagenic pruritus is characteristic and may even prevent some patients from bathing.
For scabies, there is sometimes confusion with eczema but nocturnal pruritus is a particularly suggestive clinical feature helping to distinguish it.
Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis.
Generalized pruritus is fairly common and is usually aggravated by exposure to heat or cold.
Management of pruritus is difficult, and patients rarely respond to traditional antipruritic regimens.