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It can intensify alcohol's effects and is also said to be more dangerous when taken with other depressant drugs.
The brain becomes more alert as the depressant effects of alcohol fade.
People often think the stimulant effect of caffeine counteracts the depressant effect of alcohol, but that's not true.
Because the respiratory depressant effects of methadone may last up to 48 hours, there may be a considerable time during which the victim appears to be asleep and snoring, although unwakeable.
The drug is depressant to the central nervous system at therapeutic doses.
Reversible abnormalities in ventricular function are commonly seen in subjects with chronic renal failure, an effect which has been attributed to circulating myocardial depressant factors.
Treatment with diazepam, however, had a further depressant action, practically abolishing feeding altogether.
The depressant effects of methacholine on visually evoked activity were usually accompanied by an increase in the ongoing activity of the neurone.
They have a role in patients where respiratory depressant drugs are contraindicated.
Very few women used opiates (3.6%) or depressants (2.4%) at least twice per month.
This approach allows the fetus to be studied for longer and avoids the cardiac depressant effects of anaesthetic agents.
Priming stimulation enhances the depressant effect of low-frequency repetitive transcranial magnetic stimulation.
Withdrawal from depressant drugs may result in symptoms of anxiety, panic, and even confusional states.
These actions are mediated partly by an indirect depressant action on spinal somatosensory transmission.
Their influence was assessed by rerunning analyses yielding significant effects omitting the two infants exposed to depressants and the three exposed to opiates at least twice/month during pregnancy.
Hypnotic drugs are a class on their own, but psychotropic drugs are included in classes comprising sedatives, tranquillisers and anti-depressants.
They have thus been able to offer lower charter prices to tour organisers, and this has had a depressant effect upon charter rates generally.