Especially horrific were 1796, 1799, 1805, 1809, and 1813-15, for it was then that the biggest armies were present for longest.
The biggest problem in the development of a vaccine is the identification of protective antigens.
The biggest threats to species conservation are changing land use.
Perhaps the biggest problem of all was that the fundamental stock of community song, popular as it often was, was essentially so limited and unchanging.
Generally speaking, the biggest measure in the fuzzy set is the ultimate decision.
However, the biggest financial difference is between people who receive market earnings or government transfers, and those people who have neither.
In absolute terms (in tons), the crop losses are biggest for wheat and rice.
This may be an artifact of the line of questioning which asked about the three biggest floods.