It is important to note that more effective treatment programs could include a combination of glycemic control and improved hypertension control, since both can reduce microvascular risks.
Platelets also contain dense bodies filled with vasoactive amines, such as serotonin and histamine, which increase the local microvascular permeability, allowing more inflammatory cells to infiltrate the wound.
Thus, the scenarios allow us to examine the impact of earlier diagnosis, improved treatment, or both on the development of microvascular disease.
These metabolic and inflammatory stimuli which may induce microvascular dysfunction in pre-eclampsia are proposed to arise from the placenta.
Since the coagulation cascade remains uncontrolled, it results in widespread coagulopathy and microvascular thrombosis.
The threshold for microvascular disease is clinically relevant, as the precocious development of microangiopathy is the most remarkable feature of diabetes.
Microvascular anastomoses are generally performed to the thoracodorsal or internal mammary vessels.
Microvascular complications are not explicitly incorporated into the model.
