0 a substance produced in the liver that is changed into fibrin to clot the blood when body tissue is damaged --
Fibrinogen is selectively adsorbed but the amount varies between different materials.
We discuss the possibility that modulation of fibrinogen metabolism is a factor in a recently discovered anti-atherogenic effect exerted by schistosomes.
Thus, it appears fibrinogen is not essential to the growth of the atherosclerotic plaque but it might play a modifying role.
By extrapolation, the same enzyme may be responsible for the changes observed to host blood fibrinogen.
This glycoprotein receptor binds fibrinogen resulting in platelet-fibrinogen-platelet interaction or platelet aggregation by fibrinogen crosslinking.
A family of fibrinogen-related proteins that precipitates parasite-derived molecules is produced by an invertebrate after infection.
These proteinases degraded haemoglobin and fibrinogen as well as structural proteins such as collagen and fibronectin, suggesting roles in bloodmeal digestion and tissue penetration.
Fibrinogen levels varied between 0.1 and 3.0 gm/1 (mean 1.6+0.1 gm/1) and average cryoprecipitate transfusion of 50+20 ml were required.
