Once in the nucleus, the estradiol-receptor complex exerts its effect via alterations in gene transcription, followed by changes in protein synthesis.
Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation.
Different regions in activation function-1 of the human estrogen receptor required for antiestrogen- and estradiol-dependent transcription activation.
In a 28-day pack, tablets 1-21 each contain 0.035 mg of ethinyl estradiol.
Oral ethanol (dose of 0.225 g/kg body weight) increased serum estradiol levels significantly by 27-38% [108].
Nongenomic effects of 17beta-estradiol on maturing human oocytes: relationship to oocytes developmental potential.
The minimum detectable amounts of estradiol and progesterone were 10 pg/ml and 0.5 ng/ml, respectively.
As mentioned previously, the premature adrenarche group also had significantly higher concentrations of adrenal androgens, estradiol and cor tisol.