These proteins are found in the flagella or cilia and their function is required for both assembly and normal signalling activity of this organelle.
Widely regarded as a nonfunctional, evolutionary vestigial structure, it has received little attention compared with motile cilia in organs such as the lung and brain.
This includes formation of polarised epithelia that exhibit microvilli, cilia, well-defined junctions and basolateral membrane domains.
The cilia emanate from one of the basal bodies, which are derived from the centrioles.
The larger refractile bumps at this level represent the cilia that connect outer and inner segments.
The cilia are used to latch the trap shut.
Patients have reduced or absent cilia motility, and a wide range of abnormalities in the ultrastructure of the cilia are associated with this phenotype.
An approach to digital image analysis of bending shapes of eukaryotic flagella and cilia.
