They are lytic lesions that usually contain calcified chondroid matrix (a rings and arcs pattern of calcification), except in the phalanges.
Histopathology of the lesion shows large areas of mature fibrous stroma undergoing hyaline cartilage metaplasia resulting in conspicuous lobules or gradual transformation into chondroid foci.
Both hyaline cartilage and chondroid in turn undergo calcification and endochondral cancellous bone formation mimicking epiphyseal plate-like cartilage.
Chondroid chordomas appear to have a more indolent clinical course.
Hypothecium is chondroid, and made-up of thick-walled, conglutinated cells.
Liposarcoma-like and chondroid foci can be an additional finding.
