These data show that an unknown developmentally regulated mechanism controls the duration of the two first mitoses in the mouse embryo.
The first mitosis takes 50-60 min longer than the second and third mitoses.
The first mitosis is significantly longer than the second and third mitoses.
If this ' switch ' mechanism is prevented from operating, excessive mitoses may, in certain genotypes, result in a neoplastic change.
Duration of mouse embryo mitoses between fertilised and parthenogenetically activated eggs.
The main difference between the two mitoses is the origin of chromosomes participating in the division.
These data show a peculiarity of the first mitoses of the early mouse embryos.
The number of mitoses in naive animals was 9.31 ^ 0.48 per villus-crypt unit, and slightly higher at 10.9 ^ 0.5 in infected animals.