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The tests are useful in diagnosing myopathy.
Alcoholic myopathy can occur after a bout of heavy drinking.
They studied patients with muscular dystrophies and other myopathies.
The inherited metabolic myopathies do not present for the first time in elderly people.
In the elderly, inclusion body myositis is the commonest acquired myopathy.
However, alcohol can certainly cause an acute myopathy.
Although the latter is perhaps not strictly speaking a myopathy, it will be considered here.
Proteins whose genes are mutated in myofibrillar myopathies are shown in red.
The myopathy of primary hyperthyroidism responds to removal of the adenoma.
In the elderly, inclusion body myositis is the commonest acquired myopathy; its aetiology remains uncertain.
Abnormal post-translational protein modifications also occur in myofibrillar myopathies, particularly as a result of oxidation and nitration.
Cardiac complications, especially arrhythmias and myopathy, are the main cause of death.
This is the commonest acquired myopathy in the elderly.
Because of their increasing usage, we are seeing many more cases of statin-induced myopathy.
On the other hand, chronic use of steroids is another important cause of proximal myopathy in older people.
Muscular involvement may be manifested as a distal myopathy with later involvement of the proximal muscles, or as limb-girdle myopathy with distal progression.
The inherited metabolic myopathies do not present for the first time in older people.
Management of mitochondrial myopathies remains largely symptomatic.
