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In contrast, the frequency with which cerebellar abnormalities are present in association with myelomeningocele does not appear to be gestation dependent9.
Nonetheless, there seems to a consensus that the majority of children with myelomeningocele will grow to have normal intelligence.
There appears to be an association between myelomeningocele and congenital renal anomalies.
In a review of 10 retrospective and prospective studies, cranial abnormalities were present in 232 of 234 fetuses with antenatally detected myelomeningocele.
Luthy and co-workers24 reported the outcome for 35 cases with isolated myelomeningoceles diagnosed before 24 weeks.
The direct visualisation of myelomeningocele can present a significant sonographic challenge.
Prognosis for fetuses with antenatally detected myelomeningocele 247 on the neural plate and result in additional loss of neural function.
It is, therefore, not possible to derive a precise estimate for the likelihood of neonatal survival in fetuses with an antenatally diagnosed myelomeningocele.
Prenatally detected myelomeningoceles: sonographic accuracy in estimation of the spinal level.
Diagnosis and management of prenatally detected myelomeningocele: a preliminary report.
Although many infants with myelomeningocele will survive and lead productive lives, multiple surgical procedures are often required to produce this enhanced quality of life.
In myelomeningocele, the spinal cord and its protective covering (the meninges) protrude from an opening in the spine.
In considering the prognosis for fetuses with myelomeningocele, the outcome should be considered in three categories: 1 mortality 2 intellectual disability 3 physical disability.
In patients with myelomeningocele, the level of motor paralysis was always as low as or lower than the anatomical level.
It is, therefore, appropriate to review recent outcome data for children with myelomeningocele, emphasising those studies where the diagnosis was made before delivery.
