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Even though mouse chromosome 12 (ch12) contains imprinted genes, none of them have been isolated and their putative involvement in placental development is not known.
How cells ' recognize ' the parental origin of imprinted loci remains unclear.
The ' imprintingcontrol regions ' at most imprinted loci are methylated on one of the parental alleles only.
We are producing large construct transgenic mice to study the regulatory effects of putative elements on imprinted expression.
Abstracts imprinted genes and has enriched for other known imprinted genes.
In this article, we address the physics of the generation of images of surface structures imprinted into the target back surface with laser-accelerated protons.
This novel imprinted gene is expressed exclusively or predominantly from the paternal allele in all tissues examined.
They almost invariably have caused widespread social damage, which is imprinted in the psychology of future generations.
All other imprinted genes in this cluster are paternally repressed, some ubiquitously and others in the placenta.
The evidence for the contribution of imprinted genes is summarized in the previous section.
Most autosomal genes are expressed biallelically, but some are imprinted, expressed only from one parental allele.
A characteristic of imprinted genes analysed to date is the presence of allele-specific methylation, a feature that may be used in their identification.
In contrast to their imprinted expression in mouse, these genes are expressed biallelically in human from early trophoblast through to term.
Thus, some imprinted genes are expressed from the paternally inherited chromosome and others from the maternally inherited chromosome.
Imprinted genes are associated with fetal growth and development.
