The keywords used as search terms were: radiation, erythema, acute skin reactions, adverse effects, wound management and desquamation.
Symptoms began within 4 h to 4 days (median 12 h), and virtually all cases developed swelling, erythema, and often intense pain.
It presents as an area of angry erythema often associated with white pustules.
Only 8 papers out of the total of erythema starts to occur 2-3 weeks into treatment, 31 were based on randomised trials.
The presence of overlying joint erythema and superimposed acute attacks suggest a crystal arthropathy.
For all practical purposes, erythema marginatum is seen only when carditis and/or arthritis are also present.
Patient will be informed of likely skin reactions to treatment, such as discomfort or pain, burning sensation, crusting oedema, erythema.
Subcutaneous nodules and erythema marginatum have generally been described in association with carditis.
