0 A double-blind study or trial, especially in medicine, is one in which two groups of people are studied, for example with one group taking a new drug and one group taking something else, but neither the people in the study nor the scientist or doctor knows which person is in which group.
1 used to describe a test of a new product, especially a medicine, in which one group of people is given the new product, and another group is given something that contains none of the product. Neither those being tested nor those doing the testing know which group is which:
Therapeutic efficacy of right prefrontal slow repetitive transcranial magnetic stimulation in major depression : a double-blind controlled study.
Pathological laughing and crying following stroke: validation of a measurement scale and a double-blind treatment study.
Randomized double-blind, placebo-controlled trial of high-flow inhaled oxygen in acute cluster headache.
Efficacy of pregabalin in neuropathic pain evaluated in a 12-week, randomised, double-blind, multicentre, placebo-controlled trial of flexible- and fixed-dose regimens.
Using double-blind procedures, it assessed patients a few weeks after withdrawal and then again at 6 and 12 months.
Patients from these double-blind trials could subsequently enroll in long-term open-label safety studies.
Seventy-six percent of the total study population completed the double-blind study.
Such compromise of the integrity of the double-blind in a clinical trial could lead to spurious results or an exaggeration of the treatment effect.
