Ten individuals returned both conventional and antibacterial brushes that yielded colonies.
Such ability is most likely mediated by parasite-host incompatibility, the general expression of antibacterial or detoxifying factors, and/or an inducible immune response.
The solution may lie in the design of a new generation of target-specific, antipathogenic (as opposed to antibacterial) drugs.
These antibacterial factors may play important roles in defending against infection of the amniotic fluid.
The classes of compounds considered are comprehensive and includes the recently marketed oxazolidinones, the first novel class of antibacterials to appear for decades.
In 70% of cases in this small study, antibacterial brushes carried fewer bacteria than conventional ones used by the same individuals.
Organisms with the characteristics of pseudomonads were isolated from both bacterial and antibacterial toothbrushes in this study.
The induction of an antibacterial response by microfilariae is not an artefact created by the injection procedure.
