0 a method of finding exactly how much of a substance there is in a solution by gradually adding measured amounts of another substance that reacts to it in a known way, for example by causing a colour change
Titration experiments can be performed, in which a series of patterns (of the order of 20 curves) are recorded at different substrate concentrations.
The purpose of this study was to evaluate the differences between younger and older patients during the crucial phase of opioid titration.
A small dose of loop diuretic (frusemide 20 mg. or bumetanide 0.5mg.) may be initiated and followed by careful upward titration.
He objected to the fact that stimulus dose titration was weighted as least likely to produce cognitive deficits.
Conditions for the assay were determined by a series of previous chequerboard titrations.
It has a very long half-life of 3-5 days; its significant adverse-event profile requires extremely slow dose titration every 2- 3 weeks.
Each patient will need individual monitoring during the titration phase and any time deemed appropriate when the dose is escalated.
The model has three phases: screening, upward titration, and optimal dose evaluation.
