Examples of amphiprotic

• An amphiprotic molecule (or ion) can either donate or accept a proton, thus acting either as an acid or a base.

• Amphiprotic solvents have both protophilic and protogenic properties.

• Since they can donate a proton, all amphiprotic substances contain a hydrogen atom.

• A similar type of reaction, but in which no element changes oxidation number, is the acid-base disproportionation reaction observed when an amphiprotic species reacts with itself.