0 a hormone produced in the pancreas that helps glucose (= a type of sugar) to get into the blood --
However, glucagon may act through other signal pathways.
The level of glucagon was the highest in this patient at 171 pg/ml.
Moreover, higher doses may trigger a feedback mechanism, perhaps through regulation of glucagon receptor expression.
Phosphatidylinositol-3-kinase is involved in the glucagon-induced translocation of aquaporin-8 to hepatocyte plasma membrane.
Therefore, a considerable number of glucagon antagonists and agonists have been designed as potential treatments for diabetes.
The glucagon antagonist inhibited hyperopia development, albeit only in a narrow concentration range, and at most by 50%, but not myopia development.
In their experiments, about 18% of the total glucagon could be released by high potassium stimulation.
Retinal glucagon content was about two-fold higher than choroidal content.