0 the process in which cytoplasm (= the substance surrounding a cell nucleus) in the top layer of skin cells changes into, or changes so as to contain, keratin (= a strong natural protein, the main substance that forms hair, nails, horns, feathers, etc.):
Keratinization is the acquisition of a horn-like character by the epithelial tissue in many parts of the body.
Acne may be a manifestation of a keratinization disorder.
As cells move from one epithelial layer to the next, they accumulate more and more keratin through a process called keratinization.
These changes manifest as "dry" patches and keratinization of the conjunctiva.
Androgens enhance sebum production and keratinization.
