The influence of the glucagon agonist on myopia development was much more pronounced.
There is still the possibility that the amount of glucagon precursor protein, which is most likely not detected by the radioimmunoassay, changes diurnally.
No diurnal variation in the retinal amount of glucagon was detected.
Neither glucagon nor serotonin increased in any patient.
In the present study, it was tested whether these changes are reflected in different amounts of glucagon peptide in hyperopic and myopic eyes.
The level of somatostatin and glucagon was high in this patient.
No effect of the glucagon antagonist on hyperopia development was visible at the lower and the higher dose.
Retinal glucagon content was about two-fold higher than choroidal content.
