0 a drug that reduces the level of cholesterol (= a substance containing fat in your blood that can cause heart disease) -- 抑制素（可降低血液中的胆固醇含量）
Recently, statins have been proposed as novel therapeutic drugs for multiple sclerosis, and lovastatin and simvastatin are currently tested in human trials.
The possibility of modulating raft homeostasis, using statins and synthetic sphingolipid analogues, offers new approaches for therapeutic interventions in raft-associated diseases.
Cholesterol-lowering does t herefore appear to be beneficial in the primary prevention of cerebrovascular events, though this benefit is principally regarding treatment with statin drugs.
Traditional drugs (oral contraceptives, clomiphene and antiandrogens) have been supplemented by novel pharmaceutical modalities (insulin sensitisers and statins).
Toxicity is more likely if two lipid-lowering agents are used simultaneously, or if the statin is used in combination with cyclosporin.
The association of statins with neuropathy is controversial.
Furthermore, it is known that the clinical benefit from statin treatment is related to baseline risk rather than to actual lipid levels (20).
Combination therapy (statin plus gemfribrozil) is not recommended because of the increased risk of rhabdomyolysis.
