These agents may exert their effect on local opioid receptors within the myenteric plexus of the gastrointestinal tract.
However, many factors are responsible for opioid-induced constipation.
Antisocial personality disorder was the most common personality disorder within the opioid group (28%).
In clinical practice, opioid pharmacotherapy for cancer pain hinges on finding a satisfactory balance between analgesia and side effects.
Together, current data strongly implicate glia in pathological pain, opioid tolerance, opioid dependence/withdrawal.
However, none have closely analyzed pain relief from the start of opioid administration.
Although there was an increase in the number of prescriptions, this is no way matched the number of opioid prescriptions.
Early pain relief was associated with high frequency of hospital visits before opioid administration and absence of sudden excavation within the first 2 weeks.
