Good evidence for a significant role exists for acute myeloid leukaemia and myeloma, but the role in solid tumours remains unclear.
During this latter stage, differentiation is apparently blocked, and the clonal, nonfunctional, proliferating blast cells accumulate to cause a clinical disease similar to acute leukaemia.
Removal of leukaemia inhibitory factor from the medium causes these cells to differentiate into embryoid bodies.
Malignant blood disorders with associated anaemia, such as myelodysplasia and leukaemia, become more frequent with advancing age.
He fought bravely against his leukaemia and tried as long as possible to maintain his scientific activity.
Some of the earliest were antifolates, chemically modified to increase their effectiveness in treating childhood leukaemias.
Prior conflicting results were obtained from leukaemia-derived cell lines, arrested at a single stage of haematopoiesis, and appear to be cellline-specific.
An example might be a cluster of leukaemia cases near a nuclear power plant.
