Effect of a triplex-binding ligand on parallel and antiparallel triple helices using short unmodified and arcidine-linked oligonucleotides.
The component helices might be held together only by the continuity of the strands, or they might undergo pairwise coaxial stacking.
The outer surface is formed by a -hairpin and two helices.
The catalytic subunit has an overall -helical structure containing five helices.
At # low salt concentration the junction is extended, with no stacking of helices.
As with the other structures, the junction is a right-handed antiparallel cross of pairwise, coaxially stacked helices.
The dynamic programming methods predict a larger proportion of long range helices than actually occur.
Isolated base pairs are usually unstable ; hence, helices usually consist of at least two pairs.