In centenarians, inflammaging is always accompanied by anti-inflammaging and their balance is likely to be crucial to attain healthy aging and longevity.
Other data illustrating the importance of the immune system in healthy aging come from studies on centenarians.
Self-rated health is on average somewhat lower among nonagenarians and centenarians, but the percentage reporting poor health is similar to that reported by octogenarians.
Recent work indicates that the mortality of very old people, including centenarians, has fallen considerably, at least in those countries where good data exist.
With regard to personality,33,34 centenarians showed more dominance, suspiciousness and imagination than younger old people, and exhibited more cognitive, as opposed to behavioural, coping.
The body of a centenarian is quite capable of mounting an effective inflammatory response (good adaptation and remodelling), thus becoming more robust.
The findings also illustrate that the effect differed by age, for the relationship was significant for octogenarians and nonagenarians but insignificant for centenarians.
The baseline survey tried to interview all centenarians in the included areas.
