Toxicities included hypotension (requiring use of dopamine in two patients), allergic reaction, blurred vision, neutropaenia, thrombocytopaenia and leukopaenia.
Clinicians regularly face these conditions especially in hospital settings, but remain worried about allergic reactions previously attributed to the iron dextran preparations.
Data on allergic respiratory manifestations were insufficient to draw meaningful conclusions.
Patients with seasonal allergic rhinitis, allergic to grassand/or tree-pollen, and patients with perennial allergic rhinitis, allergic to house dust mite, were included.
There were no outliers in the depressive group and the allergic control group.
The prevalence of allergic rhinitis was also more common among the reference subjects than among the exposed workers, 19 and 13 cases respectively.
The effects in allergic asthma have been questioned from time to time.
Thus, overall, the idea that helminths can protect against human allergic and autoimmune inflammatory disease is compelling.
