0 death, destruction, and other unpleasant events that cannot be avoided -- роковой конец, гибель
1 unhappiness and feeling no hope for the future -- безысходность
Unfortunately, this salvage operation is doomed to failure.
Her own attempts at intimacy always seem to be doomed.
By the end of 1991, these realities had become inescapable, thereby dooming the confederation.
Many peace conferences were doomed undertakings, which could not deliver what was expected of them.
The attempts to pronounce moral judgments are doomed to failure.
As far as relieving poverty in old age is concerned, the 1948 settlement was doomed from the outset.
The authors therefore have concluded that in such a scenario, life itself may be immortal but any individual is doomed to mortality.
The testimony, the words and actions, of this doomed character will then reveal to the audience the" natural" and inevitable decline of the disabled character.