Listeria monocytogenes infected phagocytes can initiate central nervous system infection in mice.
Astrocytes might also augment the effects of infected and/or stimulated mononuclear phagocytes through the actions of soluble factors produced by the mononuclear phagocytes acting on nearby astrocytes.
Altered cell signaling and mononuclear phagocyte deactivation during intracellular infection.
In many neurodegenerative diseases, these mononuclear phagocytes undergo a phenotypic conversion into an activated phenotype implicating the development of an inflammatory response that accelerates the disease process.
Opsonic enhancement of phagocytosis by a lectin might require that the molecules bind not only to the surface of the phagocyte but also to the foreign particle.
For the first time, we have reported selective resorption of waste materials in heterophagosomes of phagocytes.
If the phagocyte is adjacent to the engulfment target, immediate recognition can ensue.
Glial cells are therefore uniquely positioned to act as both destructive phagocytes and providers of recycled nutrients.
