0 US spelling of haemophilia (= a serious disease in which the flow of blood from someone's body cannot be stopped when they are hurt) -- hemofilia
Hemophilia therefore became known as the royal disease.
Though typically not life-threatening, joint bleeds are one of the most serious symptoms of hemophilia.
The affected individuals show a hemophilia-like bleeding phenotype.
However, scientists considered it extremely unlikely that he escaped death, due to his lifelong hemophilia.
People with hemophilia usually need a replacement of clotting factor, which is a small part of whole blood.
In other patients, especially those with moderate or mild hemophilia a later trauma will lead to the first serious bleed.
The available treatment for hemophilia at the time included transfusion of large volumes of fresh frozen plasma to replenish the missing clotting factors.
It has sometimes mistakenly been reported that he had hemophilia; this is not true.
