Here we provide the first comprehensive analysis of tissue parameters validated against histopathology as an end point.
A surrogate outcome measure in clinical trials does not need to be fully validated as a condition of drug approval.
No surface-labeling of these cytoskeletal proteins occurred, validating the surface-specificity of the labeling method.
Neurotics in modern society are those whose ways of seeing the world are not generally socially validated.
Whatever the origin of the benefit, it is its existence which validates the trust.
Our aesthetic evaluation is validated in three ways.
The first of these options is clearly one that - in principle - could be validated with empirical evidence.
There is some suggestion that the early starter trajectory might be validated by prevention trials.