Dissemination may occur to multiple organs including the skin, oesophagus, liver, lungs, adrenal glands, pancreas, bowel, kidneys, bone marrow and joints.
Two fetuses had a pancreas of half normal size which lacked any inferior lobe.
There is evidence t o show that pancreas transplantation will improve autonomic neuropathy, in addition to its beneficial effects on normalising blood glucose.
There is a chronic shortage of human pancreas tissue suitable for either whole pancreas or islet transplantation.
Figure 2 shows the technique that is currently used for the production of islets from human cadaveric pancreas.
In summary, the supply of human pancreases and/or islets must increase if this technique is to meet the needs of this patient group worldwide.
Transplantation of pancreas and lungs has recently been assessed under this program, and coverage decisions have recently been made.
It also plays a role in b-cell differentiation, pancreas development and glucose homeostasis.