0 to touch or hold someone roughly and with force, often when taking them somewhere:
There were complaints that the police had manhandled some of the demonstrators.
1 to move something using the physical strength of the body:
2 to handle someone with force or push someone around, often when taking the person somewhere:
We can complete it step by step however long the road is and it can't be completed however short the road is if you don't even mark your footprint.